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Merck
CN

880170P

Avanti

C8 PEG2000 Ceramide

Avanti Research - A Croda Brand 880170P, powder

别名:

N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}

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About This Item

UNSPSC代码:
12352211
NACRES:
NA.25

表单

powder

包装

pkg of 1 × 25 mg (880170P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 880170P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)COC(CCC(OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O.C=C

InChI

1S/C119H233NO51.C2H4/c1-4-6-8-10-11-12-13-14-15-16-17-19-20-22-116(121)115(120-117(122)23-21-18-9-7-5-2)114-169-118(123)24-25-119(124)171-170-113-112-168-111-110-167-109-108-166-107-106-165-105-104-164-103-102-163-101-100-162-99-98-161-97-96-160-95-94-159

InChI key

QXQSNNJSIRCDPD-OTOABLIDSA-N

一般描述

C8 PEG2000 Ceramide, also known as N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}, is a polyethylene glycol (PEG)-modified lipid. Ceramide-PEGylated lipoplexes deliver siRNA to targeted sites more efficiently than 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEGylated lipoplexes.

应用

C8 PEG2000 Ceramide, or N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]} is suitable for PEGylated lipoplexes preparation.

包装

5 mL Amber Glass Screw Cap Vial (880170P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3


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Anna Lechanteur et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 93, 493-503 (2016-09-07)
The delivery of small interfering RNA (siRNA) is an attractive therapeutic approach to treat several pathologies, such as viral infections or cancers. However, the stability and the efficacy of these biotherapies are still a major obstacle to their use. Cationic

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