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Merck
CN
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文件

安全信息

878124C

Avanti

C16-22:6 PC

Avanti Polar Lipids 878124C

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别名:
1-O-hexadecyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine
经验公式（希尔记法）:
C46H82NO7P
CAS号:
132213-85-5
分子量:
792.12
UNSPSC代码:
12352211
NACRES:
NA.25

形式

liquid

包装

pkg of 1 × 1 mL (878124C-5mg)

制造商/商品名称

Avanti Polar Lipids 878124C

浓度

5 mg/mL (878124C-5mg)

脂质类型

phosphoglycerides
bioactive lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C46H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-26-27-29-31-33-35-37-39-46(48)54-45(44-53-55(49,50)52-42-40-47(3,4)5)43-51-41-38-36-34-32-30-28-21-19-17-15-13-11-9-7-2/h8,10,14,16,20,22,24-25,27,29,33,35,45H,6-7,9,11-13,15,17-19,21,23,26,28,30-32,34,36-44H2,1-5H3/b10-8-,16-14-,22-20-,25-24-,29-27-,35-33-/t45-/m1/s1

InChI key

QQQQNYAHSSIZBU-HIQXTUQZSA-N

相关类别

一般描述

Phophotidylcholine (PC) is a glycerophospholipid. It is synthesized in by the CDP-choline pathway or Kennedy pathway. PC is present at higher concentrations in all mammalian cells and organelles.

应用

C16-22:6 PC has been used as a lipid reference standard in matrix assisted laser desorption/ionization- time-of-light (MALDI-TOF) mass spectrometry.

生化/生理作用

Phophotidylcholine (PC) plays a role in cellular and human physiology. It is a housekeeping component that is involved in maintaining the integrity of cell membranes. PC is an essential component for the synthesis of very low density lipoprotein (VLDL) from hepatocytes. It is also implicated in myelinating the nerve cells.

包装

5 mL Clear Glass Sealed Ampule (878124C-5mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

易制毒化学品（2类）
危险化学品

分析证书(COA)

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访问文档库

Characteristic oxidation products of choline plasmalogens are detectable in cattle and roe deer spermatozoa by MALDI-TOF mass spectrometry
Fuchs B, et al.
Lipids, 42(11), 991-998 (2007)
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes (2017)
From yeast to humans-roles of the Kennedy pathway for phosphatidylcholine synthesis
McMaster C R
Febs Letters, 592(8), 1256-1272 (2018)
A review on phospholipids and their main applications in drug delivery systems
Li J, et al.
Asian Journal of Pharmaceutical Sciences , 10(2), 81-98 (2015)

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