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表单
powder
包装
pkg of 1 × 5 mg (870852P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 870852P
脂质类型
bioactive lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
C[N+](C)(C)C[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CC([O-])=O
InChI
1S/C25H47NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4/h12-13,23H,5-11,14-22H2,1-4H3/b13-12-
InChI key
IPOLTUVFXFHAHI-SEYXRHQNSA-N
应用
C18:1（Δ9-顺式）肉碱可用作内标，以通过串联质谱法（MS/MS）测量血浆样品中肉碱的水平。
生化/生理作用
C18:1（Δ9-顺式）肉毒碱或油酰基L-肉碱是一种内源性酰基肉碱。它是甘氨酸转运蛋白2（GLYT2）的潜在非竞争性抑制剂。油酰基L-肉碱被用作治疗疼痛的有效治疗剂。
包装
5 mL透明玻璃密封安瓿（870852P-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
J E Carland et al.
British journal of pharmacology, 168(4), 891-902 (2012-09-18)
Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2. Selective inhibitors of GlyT1 have been developed for the treatment of schizophrenia, whilst selective inhibitors of GlyT2 are analgesic in animal models
Lawrence C Johnson et al.
Clinical science (London, England : 1979), 132(16), 1765-1777 (2018-06-20)
Advancing age is associated with impairments in numerous physiological systems, leading to an increased risk of chronic disease and disability, and reduced healthspan (the period of high functioning healthy life). The plasma metabolome is thought to reflect changes in the
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