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形式
powder
包装
pkg of 1 × 5 mg (870850P-5mg)
制造商/商品名称
Avanti Polar Lipids 870850P
脂质类型
bioactive lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O
InChI
1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1
InChI key
FUJLYHJROOYKRA-QGZVFWFLSA-N
一般描述
C12 Carnitine or lauroyl L-carnitine, is a lauric acid-derived serum acylcarnitine. It mediates obesity-induced inflammation in adipose. Elevated levels of lauroyl carnitine in carcinoma-associated fibroblasts (CAF)-adipose tissue acts as a biomarker for obesity, insulin resistance and inflammation.
应用
C12 Carnitine or lauroyl L-carnitine has been used to investigate its effect on the glycine transporters activity. It has also been used to study its effect on pro-inflammatory activation of macrophages.
包装
5 mL Amber Glass Screw Cap Vial (870850P-5mg)
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Brante P Sampey et al.
PloS one, 7(6), e38812-e38812 (2012-06-16)
Obesity has reached epidemic proportions worldwide. Several animal models of obesity exist, but studies are lacking that compare traditional lard-based high fat diets (HFD) to "Cafeteria diets" (CAF) consisting of nutrient poor human junk food. Our previous work demonstrated the
Oleoyl-l-carnitine inhibits glycine transport by G ly T 2
Carland JE, et al.
British Journal of Pharmacology, 168(4), 891-902 (2013)
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