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Merck
CN

870720P

Avanti

20:0 Coenzyme A

Avanti Polar Lipids 870720P, powder

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别名:
arachidoyl Coenzyme A (ammonium salt)
经验公式(希尔记法):
C41H83N10O17P3S
分子量:
1113.14
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 5 mg (870720P-5mg)

制造商/商品名称

Avanti Polar Lipids 870720P

应用

lipidomics

脂质类型

coenzymes

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

InChI

1S/C41H74N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-32(50)69-25-24-43-31(49)22-23-44-39(53)36(52)41(2,3)27-62-68(59,60)65-67(57,58)61-26-30-35(64-66(54,55)56)34(51)40(63-30)48-29-47-33-37(42)45-28-46-38(33)48;;;/h28-30,34-36,40,51-52H,4-27H2,1-3H3,(H,43,49)(H,44,53)(H,57,58)(H,59,60)(H2,42,45,46)(H2,54,55,56);3*1H3/t30-,34?,35+,36+,40-;;;/m1.../s1

InChI key

FCQFGWHSMZFGCX-LEEULGQNSA-N

一般描述

20:0 Coenzyme A, also known as arachidoyl Coenzyme A belongs to the group of long-chain acyl-CoAs. It serves as a key lipid metabolite.

应用

20:0 Coenzyme A has been used as an internal standard for measuring long-chain acyl-coenzyme A concentrations and enrichment by liquid chromatography/tandem mass spectrometry. It has also been used as a substrate in ceramide synthase assay.

包装

5 mL Amber Glass Screw Cap Vial (870720P-5mg)

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Katharina Vollheyde et al.
Lipids, 55(5), 479-494 (2020-05-21)
Wax esters (WE) belong to the class of neutral lipids. They are formed by an esterification of a fatty alcohol and an activated fatty acid. Dependent on the chain length and desaturation degree of the fatty acid and the fatty
Agnieszka U Blachnio-Zabielska et al.
Rapid communications in mass spectrometry : RCM, 25(15), 2223-2230 (2011-07-08)
Long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA) are the activated forms of long-chain fatty acids and serve as key lipid metabolites. Excess accumulation of intracellular LCACoA, diacylglycerols (DAGs) and ceramides may create insulin resistance with respect to glucose metabolism. We present a
Evgeny V Berdyshev et al.
The Journal of biological chemistry, 284(9), 5467-5477 (2009-01-03)
Novel immunomodulatory molecule FTY720 is a synthetic analog of myriocin, but unlike myriocin FTY720 does not inhibit serine palmitoyltransferase. Although many of the effects of FTY720 are ascribed to its phosphorylation and subsequent sphingosine 1-phosphate (S1P)-like action through S1P(1,3-5) receptors

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