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870716P

Avanti

16：0辅酶A

Avanti Polar Lipids 870716P, powder

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别名:
棕榈酰辅酶A铵盐
经验公式（希尔记法）:
C37H75N10O17P3S
CAS号:
799812-86-5
分子量:
1057.03
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 10 mg (870716P-10mg)
pkg of 1 × 25 mg (870716P-25mg)
pkg of 1 × 5 mg (870716P-5mg)

制造商/商品名称

Avanti Polar Lipids 870716P

应用

lipidomics

脂质类型

coenzymes

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

InChI

1S/C37H66N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44;;;/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52);3*1H3/t26-,30?,31+,32+,36-;;;/m1.../s1

InChI key

VJXJWGKNGIGUQX-AUCFWDBISA-N

相关类别

一般描述

16:0辅酶A，又称为棕榈酰辅酶A，是含量最为丰富的酰基-CoA，是β-氧化的第一轮产物。它可作为反应底物，在蛋白酰基转移酶催化下通过棕榈酰化反应将棕榈酰基转移到靶标蛋白的游离巯基上。

应用

16:0辅酶A已用作：
  • 分枝杆菌细胞内棕榈酰-CoA质谱法定量分析的标准品
  • 蛋白体外结合实验的结合缓冲液组分
  • 丝氨酸棕榈酰基转移酶的测定底物

包装

5 mL棕色玻璃螺旋盖小瓶 (870716P-10mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-25mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-5mg)

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Cheryl Budde et al.
Methods (San Diego, Calif.), 40(2), 143-150 (2006-10-03)
Palmitoylation enhances membrane association and plays a role in the subcellular trafficking and signaling function of proteins. Unlike other forms of protein lipidation, such as prenylation and myristoylation, palmitoylation is reversible and can therefore play a regulatory role. Enzyme activities
Matías Cabruja et al.
Applied microbiology and biotechnology, 100(16), 7239-7248 (2016-06-09)
Acyl-CoAs are crucial compounds involved in essential metabolic pathways such as the Krebs cycle and lipid, carbohydrate, and amino acid metabolisms, and they are also key signal molecules involved in the transcriptional regulation of lipid biosynthesis in many organisms. In
Oshrit Ben-David et al.
The Journal of biological chemistry, 286(34), 30022-30033 (2011-06-28)
Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin. We now characterize the biochemical, histological, and behavioral abnormalities in the brain of a mouse lacking very long acyl (C22-C24) chain SLs. This mouse
Analysis of coenzyme A activated compounds in actinomycetes
Cabruja M, et al.
Applied Microbiology and Biotechnology, 100(16), 7239-7248 (2016)
Jeong-Won Nam et al.
The Plant cell, 32(4), 820-832 (2020-02-16)
Acyl carrier proteins (ACPs) are the scaffolds for fatty acid biosynthesis in living systems, rendering them essential to a comprehensive understanding of lipid metabolism. However, accurate quantitative methods to assess individual acyl-ACPs do not exist. We developed a robust method
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