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Merck
CN

870520P

Avanti

18:1 CDP DG

Avanti Research - A Croda Brand

别名:

1,2-二油酰-sn-甘油-3-(胞苷二磷酸)(铵盐)

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About This Item

经验公式(希尔记法):
C48H91N5O15P2
分子量:
1040.21
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

表单

powder

包装

pkg of 1 × 25 mg (870520P-25mg)
pkg of 1 × 5 mg (870520P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand

脂质类型

phosphoglycerides
bioactive lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C48H85N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56;;/h17-20,35-36,40-41,45-47,54-55H,3-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56);2*1H3/b19-17-,20-18-;;/t40-,41-,45+,46?,47-;;/m1../s1

InChI key

NECNTGAHQCHVGS-BQGZBBTBSA-N

应用

18:1 CDP DG(1,2-二油酰基-sn-甘油-3-(胞苷二磷酸))可用于制备脂质体。

生化/生理作用

18:1 CDP DG(1,2-二油酰基-sn-甘油-3-(胞苷二磷酸))是二酰基甘油衍生物。它充当磷脂酰丝氨酸合酶(Pss)的底物,该酶参与各种生物中磷脂的合成。CDP-二酰基甘油用作磷脂酰肌醇生物合成的前体。CDP-二酰基甘油信号通路失调导致抑郁。

包装

5 mL透明玻璃密封安瓿(870520P-25mg)
5 mL透明玻璃密封安瓿(870520P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

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Andrew G Reidenbach et al.
Cell chemical biology, 25(2), 154-165 (2017-12-05)
Human COQ8A (ADCK3) and Saccharomyces cerevisiae Coq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain unclear, in part due to lack
Kimberly R Tyeryar et al.
BMC neuroscience, 9, 12-12 (2008-01-26)
Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple
Ru-Yin Huang et al.
Current microbiology, 77(5), 710-715 (2020-01-04)
Phosphatidylserine synthase (Pss) is involved in the metabolic pathway in phospholipid synthesis in different organisms. In this study, Pss expression in Vibrio parahaemolyticus was verified through liquid chromatography tandem-mass spectrometry. To analyze the characteristics of Pss, the recombinant Pss was

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