推荐产品
形式
liquid
包装
pkg of 1 × 1 mL (870440C-1mg)
制造商/商品名称
Avanti Polar Lipids 870440C
浓度
1 mg/mL (870440C-1mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCOP(O)([O-])=O.[Na+]
一般描述
Anandamide (AEA) is an endogenous ligand for cannabinoid receptors. It is an N-acyl ethanolamide derivative of C20,4 fatty acid. AEA is a lipid neurotransmitter. It is synthesized and released by the neurons in the brain and macrophages. AEA is a lipophilic and poorly water-soluble compound. Anandamide phosphate (pAEA) is dephosphorylated by phosphatase to yield anandamide.{56)
生化/生理作用
Anandamide (AEA) is involved in many physiological and pathophysiological functions, such as regulation of energy consumption and balance. It also plays an important role in initiation and control of inflammation and modulatory effects on sensory and autonomic nerve signaling.
包装
5 mL Amber Screw Cap Bottle with Foil Bag Argon Overseal (870440C-1mg)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
法规信息
新产品
Multiple pathways involved in the biosynthesis of anandamide
Liu J, et al.
Neuropharmacology, 54(1), 1-7 (2008)
Anandamide prodrugs: 1. Water-soluble phosphate esters of arachidonylethanolamide and R-methanandamide
Juntunen J, et al.
European Journal of Pharmaceutical Sciences, 19(1), 37-43 (2003)
Anandamide and its metabolites: what are their roles in the kidney?
Ritter J K, et al.
Frontiers in Bioscience, 8(2-3), 264-264 (2016)
Anandamide receptors
Di Marzo V, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 66(2-3), 377-391 (2002)
Targeting fatty-acid amide hydrolase with prodrugs for CNS-selective therapy
Meinig J M, et al.
ACS Chemical Neuroscience, 8(11), 2468-2476 (2017)
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