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表单
powder
包装
pkg of 1 × 5 mg (870432P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 870432P
脂质类型
bioactive lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
O=C(CCCCCCC/C=C\CCCCCCCC)NCCO
InChI
1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
InChI key
BOWVQLFMWHZBEF-KTKRTIGZSA-N
一般描述
Anandamide is an endocannabinoid. It acts as a ligand for cannabinoid (CB) receptors CB1 and CB2 in the brain and peripheral tissues. It is synthesized from glycerophospho-N-arachidonoylethanolamine (GP-NArE) precursor by the reaction catalyzed by glycerophosphodiesterase 1.
生化/生理作用
Anandamide plays a vital role in various processes including inflammation, pain, and appetite.
包装
5 mL Clear Glass Sealed Ampule (870432P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
Long J, et al.
Nature Chemical Biology, 5(1), 37-37 (2009)
Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain
Astarita G, et al.
Journal of Lipid Research, 49(1), 48-57 (2008)
Mohammed K Hankir et al.
Frontiers in neuroscience, 10, 620-620 (2017-01-31)
Brain μ-opioid receptors (MORs) stimulate high-fat (HF) feeding and have been implicated in the distinct long term outcomes on body weight of bariatric surgery and dieting. Whether alterations in fat appetite specifically following these disparate weight loss interventions relate to
Mohammad Younus et al.
Langmuir : the ACS journal of surfaces and colloids, 32(35), 8942-8950 (2016-08-16)
Oleoylethanolamide (OEA) is an endogenous lipid with neuroprotective properties and the fortification of its concentration in the brain can be beneficial in the treatment of many neurodegenerative disorders. However, OEA is rapidly eliminated by hydrolysis in vivo, limiting its therapeutic
Gabriel M Simon et al.
The Journal of biological chemistry, 283(14), 9341-9349 (2008-01-30)
Anandamide (AEA) is an endogenous ligand of cannabinoid receptors and a well characterized mediator of many physiological processes including inflammation, pain, and appetite. The biosynthetic pathway(s) for anandamide and its N-acyl ethanolamine (NAE) congeners remain enigmatic. Previously, we proposed an
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