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Merck
CN

870431P

Avanti

C17:1 anandamide

Avanti Polar Lipids 870431P, powder

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别名:
10Z-heptadecenoylethanolamide
经验公式(希尔记法):
C19H37NO2
分子量:
311.50
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 5 mg (870431P-5mg)

制造商/商品名称

Avanti Polar Lipids 870431P

脂质类型

bioactive lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

O=C(CCCCCCCC/C=C\CCCCCC)NCCO

一般描述

C17:1 anandamide, also known as 10Z-heptadecenoylethanolamide, is a N-acyl ethanolamide derivative of heptadecanoic acid.

应用

C17:1 anandamide or 10Z-heptadecenoylethanolamide has been used as an internal standard in mass spectrometry analysis for the measurement of 2-arachidonoyl glycerol (2-AG) in brain tissue. It has also been used as a substrate for N-acylethanolamine acid amidase (NAAA) enzyme.

包装

5 mL Clear Glass Sealed Ampule (870431P-5mg)

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Yoki Nakamura et al.
eLife, 8 (2019-10-10)
Cocaine is an addictive drug that acts in brain reward areas. Recent evidence suggests that cocaine stimulates synthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in midbrain, increasing dopamine neuron activity via disinhibition. Although a mechanism for cocaine-stimulated 2-AG synthesis is known
Oscar Sasso et al.
Pain, 154(3), 350-360 (2012-12-12)
Fatty acid ethanolamides (FAEs), which include palmitoylethanolamide (PEA) and oleoylethanolamide (OEA), are endogenous agonists of peroxisome proliferator-activated receptor-α (PPAR-α) and important regulators of the inflammatory response. They are degraded in macrophages by the lysosomal cysteine amidase, N-acylethanolamine acid amidase (NAAA).
Natsuo Ueda et al.
Biochimica et biophysica acta, 1801(12), 1274-1285 (2010-08-26)
Ethanolamides of different long-chain fatty acids constitute a class of endogenous lipid molecules generally called N-acylethanolamines (NAEs). They contain N-arachidonoylethanolamine (anandamide), N-palmitoylethanolamine, and N-oleoylethanolamine, which receive considerable attention because of their actions as an endogenous cannabinoid receptor ligand (endocannabinoid), an

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