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Merck
CN
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文件

870225P

Avanti

16:0 Succinyl PE

Avanti Polar Lipids 870225P, powder

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别名:
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (sodium salt)
经验公式（希尔记法）:
C41H77NO11PNa
CAS号:
186800-61-3
分子量:
814.01
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 25 mg (870225P-25mg)
pkg of 1 × 500 mg (870225P-500mg)

制造商/商品名称

Avanti Polar Lipids 870225P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCN([H])C(CCC(O)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C41H78NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-40(46)50-35-37(36-52-54(48,49)51-34-33-42-38(43)31-32-39(44)45)53-41(47)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h37H,3-36H2,1-2H3,(H,42,43)(H,44,45)(H,48,49);/q;+1/p-1/t37-;/m1./s1

InChI key

CSBBOJBLMMDIFP-GKEJWYBXSA-M

相关类别

一般描述

16:0 Succinyl PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)(DPPE), is a head group modified functionalized lipid. Functionalized lipids act as reporter molecules.

生化/生理作用

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (DPPE) is used in production of PHEA-EDA-DPPE-GAL copolymer. This copolymer is used in preparation of ribavirin (RBV) tripalmitate-loaded nanoparticles, that act as hepatic cell-targeted carriers for hepatitis C treatment.

包装

20 mL Clear Glass Screw Cap Vial (870225P-500mg)
5 mL Amber Glass Screw Cap Vial (870225P-25mg)

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Emanuela Fabiola Craparo et al.
Journal of biomedical nanotechnology, 9(6), 1107-1122 (2013-07-19)
In this paper, we describe the preparation of liver-targeted nanoparticles potentially able to carry to hepatocytes a ribavirin (RBV) prodrug, exploiting the presence of carbohydrate receptors in the liver (i.e., ASGPR in hepatocytes). These particles were obtained starting from a
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as

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