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Merck
CN

870128P

Avanti

16:0 DBCO PE

Avanti Research - A Croda Brand 870128P, powder

别名:

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl

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About This Item

经验公式(希尔记法):
C56H90N3O10P
分子量:
996.30
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 25 mg (870128P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 870128P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

一般描述

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE) is a head group modified lipid containing dibenzocyclooctyne (DBCO). It is a widely used reagent in click chemistry.

应用

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE or DPPE-DBCO) has been used in preparation of DBCO-presenting lipid bilayers. It has also been used in preparation of clickable cubosomes for antibody-free drug targeting and imaging applications.

包装

5 mL Amber Glass Screw Cap Vial (870128P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

闪点(°F)

No data available

闪点(°C)

No data available


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Nicolas Alcaraz et al.
Bioconjugate chemistry, 29(1), 149-157 (2017-11-29)
The combination of copper-free click chemistry with metabolic labeling offers new opportunities in drug delivery. The objective of this study was to determine whether cubosomes functionalized with azide or dibenzocyclooctyne (DBCO) groups are able to undergo copper-free click chemistry with
Simon Finn Mayer et al.
Biochimica et biophysica acta. Biomembranes, 1861(10), 183023-183023 (2019-07-22)
Pore-forming antimicrobial peptides (AMPs) are attracting interest as cytolytic antibiotics and drug delivery agents with potential use for targeting cancer cells or multidrug-resistant pathogens. Ceratotoxin A (CtxA) is an insect-derived cytolytic AMP with 36 amino acids that is thought to

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