所有图片(1)
别名:
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt)
经验公式（希尔记法）:
C51H84N2O11PNa
推荐产品
形式
powder
包装
pkg of 1 × 100 mg (870013P-100mg)
pkg of 1 × 25 mg (870013P-25mg)
制造商/商品名称
Avanti Polar Lipids 870013P
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCCNC(CCCC(C=C1)=CC=C1N(C(C=C2)=O)C2=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C51H85N2O11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-50(57)61-42-46(64-51(58)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)43-63-65(59,60)62-41-40-52-47(54)31-29-30-44-34-36-45(37-35-44)53-48(55)38-39-49(53)56;/h34-39,46H,3-33,40-43H2,1-2H3,(H,52,54)(H,59,60);/q;+1/p-1/t46-;/m1./s1
InChI key
REKODAHLWDSEBQ-FYQWNKFKSA-M
一般描述
16:0 maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) also known as, DPPE-maleimide contains maleimide, which is a thiol-reactive moiety and a good electrophile. MPB PE is implicated in liposome preparation.
应用
16:0 maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) is suitable for use:
- for preparation of maleimide-functionalized microbubbles
- for lipidation of ligand binding site-1 (LBS-1) peptide and GABAA receptor-associated protein (GABARAP) involved in liposome and autophagosome formation, respectively
- for preparation of ligand-conjugated acoustic perfluorocarbon emulsion nanoparticles
包装
5 mL Amber Glass Screw Cap Vial (870013P-100mg)
5 mL Amber Glass Screw Cap Vial (870013P-25mg)
WGK
WGK 3
Preparation of a functional GABARAP--lipid conjugate in nanodiscs and its investigation by solution NMR spectroscopy
Ma P, et al.
Chembiochem, 11(14), 1967-1970 (2010)
Liposomes as tools in basic research and industry (1994)
Grafting of abciximab to a microbubble-based ultrasound contrast agent for targeting to platelets expressing GP IIb/IIIa--characterization and in vitro testing
Della MA, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 68(3), 555-564 (2008)
Novel MRI contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaques
Flacke S, et al
Circulation, 104(11), 1280-1285 (2001)
Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding
Seeley S, et al.
Chemistry & Biology, 10(11), 1033-1041 (2003)
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