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Merck
CN

860871P

Avanti

C24:1 Mono-sulfo galactosyl (alpha) ceramide (d18:1/24:1)

Avanti Polar Lipids 860871P, powder

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别名:
3-O-Sulfo-D-galactosyl-α1,1′-N-Nervonoyl-D-erythro-sphingsoine (ammonium salt), (synthetic)
经验公式(希尔记法):
C48H94N2O11S
分子量:
907.33
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 1 mg (860871P-1mg)

制造商/商品名称

Avanti Polar Lipids 860871P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

一般描述

C24:1 Mono-sulfo galactosyl (a) ceramide (d18:1/24:1), also known as 3-O-Sulfo-D-galactosyl-a 1,1′-N-Nervonoyl-D-erythro-sphingsoine, is a synthetic sulfatide that belongs to the class of glycosphingolipids.

生化/生理作用

Sulfatides play a crucial role in various cellular processes such as protein trafficking, signal transduction and neuronal cell differentiation. Accumulation of 3-O-Sulfogalactosylceramides (sulfatides), due to the deficiency of arylsulfatase A, leads to genetic disease metachromatic leukodystrophy.

包装

5 mL Amber Glass Screw Cap Vial (860871P-1mg)

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

法规信息

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分析证书(COA)

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Analysis of complex lipidomes
Uphoff A, et al.
Medical Applications of Mass Spectrometry (2008)
Yanli Cui et al.
Glycoconjugate journal, 25(2), 147-155 (2007-08-19)
3-O-Sulfogalactosylceramides (sulfatides) accumulate in the genetic disease metachromatic leukodystrophy which is due to a defect in the catabolic enzyme, arylsulfatase A. Clinical diagnosis is usually confirmed by in vitro enzymatic deficiency of arylsulfatase A activity. The diagnosis may be complicated

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