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Merck
CN

860837P

Avanti

CER7-2′R,6R(d9)

Avanti Research - A Croda Brand 860837P, powder

别名:

N(2′-(R)-hydroxypalmitoyl(d9)) 6R-hydroxysphingosine

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About This Item

经验公式(希尔记法):
C34H58D9NO5
分子量:
578.95
UNSPSC代码:
12352100
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 1 mg (860837P-1mg)

制造商/商品名称

Avanti Research - A Croda Brand 860837P

运输

dry ice

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCC[C@@H](O)/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)CO

一般描述

6-Hydroxysphingosine is one of the moieties that make up the class of ceramides, which are lipids localized to stratum corneum. It is formed due to incorporation of hydroxyl group to long chain bases.

应用

N(2′-(R)-hydroxypalmitoyl(d9)) 6R-hydroxysphingosine (CER7-2′R,6R(d9)) has been used as an internal standard for qualitative analysis of stratum corneum (SC) ceramides in humans and mice by liquid chromatography–mass spectrometry (LC-MS)/MS.

生化/生理作用

6-Hydroxysphingosine is one of the sphingoid bases in skin.

包装

5 mL Amber Glass Screw Cap Vial (860837P-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

法规信息

美国出口管控1C298产品

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Identification of lipids of the stratum corneum by high performance thin layer chromatography and mass spectrometry
Jamin EL, et al.
Eur. J. Mass Spectrom., 2018, 1469066718815380-1469066718815380 (2018)
Principles and Practice of Skin Toxicology, 21-21 (2008)
Lipids and the Permeability and Antimicrobial Barriers of the Skin
Wertz Philip W
Journal of Lipids, 2018 (2018)
Momoko Kawana et al.
Journal of lipid research, 61(6), 884-895 (2020-04-09)
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite

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