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关于此项目
经验公式（希尔记法）:
C34H58D9NO5
化学文摘社编号:
分子量:
578.95
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
产品名称
CER7-2′R,6R(d9), Avanti Research™ - A Croda Brand 860837P, powder
InChI key
FDCYWFADVRIZMH-LZVCNZPASA-N
SMILES string
CCCCCCCCCCCC[C@@H](O)/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)CO
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860837P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860837P
shipped in
dry ice
storage temp.
−20°C
Application
N(2′-(R)-hydroxypalmitoyl(d9)) 6R-hydroxysphingosine (CER7-2′R,6R(d9)) has been used as an internal standard for qualitative analysis of stratum corneum (SC) ceramides in humans and mice by liquid chromatography–mass spectrometry (LC-MS)/MS.
Biochem/physiol Actions
6-Hydroxysphingosine is one of the sphingoid bases in skin.
General description
6-Hydroxysphingosine is one of the moieties that make up the class of ceramides, which are lipids localized to stratum corneum. It is formed due to incorporation of hydroxyl group to long chain bases.
Packaging
5 mL Amber Glass Screw Cap Vial (860837P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
法规信息
美国出口管控产品
此项目有
Lipids and the Permeability and Antimicrobial Barriers of the Skin
Wertz Philip W
Journal of Lipids, 2018 (2018)
Identification of lipids of the stratum corneum by high performance thin layer chromatography and mass spectrometry
Jamin EL, et al.
Eur. J. Mass Spectrom., 2018, 1469066718815380-1469066718815380 (2018)
Principles and Practice of Skin Toxicology, 21-21 (2008)
Momoko Kawana et al.
Journal of lipid research, 61(6), 884-895 (2020-04-09)
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite
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