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Merck
CN

860685P

Avanti

Lyso-SM-d9

powder, Avanti Polar Lipids (860685P)

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别名:
Sphingosylphosphorylcholine-d9
经验公式(希尔记法):
C23H40D9N2O5P
分子量:
473.67
UNSPSC代码:
12352211
NACRES:
NA.12

检测方案

99% (TLC)

形式

powder

包装

pkg of 1 × 1 mg (860685P-1MG)

制造商/商品名称

Avanti Polar Lipids (860685P)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O

一般描述

Lyso-SM-d9 is a deuterated lyso-SM. Lyso sphingomyelin (Lyso-SM) is obtained from sphingomyelin due to the cleavage of N-acyl linkage of ceramides in sphingomyelin by the help of hydrolase.

生化/生理作用

Lyso sphingomyelin (Lyso-SM) functions as lipid mediators. It plays a vital role in cellular functioning of the skin, blood vessels, brain and heart. It also helps in the functioning of the immune system.

包装

5 mL Amber Glass Screw Cap Vial

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms.
Ito M
The Journal of Biological Chemistry, 270(41), 24370-24374 (1995)
Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients
Chuang W L, et al.
Molecular Genetics and Metabolism, 111(2), 209-211 (2014)

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