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检测方案
99% (TLC)
形式
powder
包装
package of 1 × 100 μg (860682P-100UG)
制造商/商品名称
Avanti Polar Lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
O[C@H]1[C@H](OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O)[C@H]2O)O[C@H]3O[C@H](CO)[C@@H]([C@H](O)[C@H]3O)O)[C@@H]1O
一般描述
Globotriaosylsphingosine-d7 (Lyso GB3-d7) is a deuterated derivative of globotriaosylsphingosine (Lyso-GB3). Lyso GB3 is a bioactive glycolipid circulating in the blood. It is a deacylated form of globotriaosylceramide.
生化/生理作用
Globotriaosylsphingosine (Lyso GB3) accumulates to a greater extent in fabry disease.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (860682P-100UG)
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Lyso-Gb3 activates Notch1 in human podocytes
Sanchez N, et al.
Human Molecular Genetics, 24(20), 5720-5732 (2015)
The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain
Choi L, et al.
Neuroscience Letters, 594, 163-168 (2015)
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