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经验公式(希尔记法):
C33H58 D7NO3
化学文摘社编号:
分子量:
530.92
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
C15 神经酰胺-d7 (d18:1-d7/15:0), Avanti Research™ - A Croda Brand 860681P, powder
InChI key
HBULQAPKKLNTLT-CVNQHAACSA-N
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860681P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860681P
shipped in
dry ice
storage temp.
−20°C
Application
C15 神经酰胺-d7(d18:1-d7/15:0)被用作通过thermo Q-Exactive四极杆-静电场轨道阱质谱测量斑马鱼大脑和人胚胎肾细胞系(HEK293)中C32–C34神经酰胺的标准品。它还用于通过超高效液相色谱-串联质谱法(UHPLC/MS/MS)测量小鼠右下颌下腺中鞘脂的浓度。
Biochem/physiol Actions
神经酰胺可用作几种鞘脂的前体。神经酰胺在细胞分化,增殖和凋亡中起重要作用。此外,它们还充当细胞信号传导中的次级递质。
General description
C15神经酰胺(d18:1/15:0)是一种含有鞘氨醇和十五烷酸的合成神经酰胺。C15神经酰胺-d7(d18:1-d7/15:0)是C15神经酰胺(d18:1/15:0)的氘代衍生物。
Packaging
5 mL棕色玻璃螺旋盖小瓶(860681P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Claude Vieu et al.
Journal of lipid research, 43(3), 510-522 (2002-03-15)
This study reports a single-step analysis of the molecular species of endogenous ceramides and of the ceramide moiety of sphingomyelins in biological samples, using gas liquid chromatography (GLC). Silylated sphingomyelins were quantitatively converted to monosilylated ceramide upon injection into GLC
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Anna Zalewska et al.
Biomolecules, 9(12) (2019-12-19)
This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the submandibular gland mitochondria of mice with insulin resistance (IR). The experiment was conducted on 20 male C57BL/6 mice
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
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