形式
powder
包装
pkg of 1 × 1 mg (860679P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860679P
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
一般描述
C24:1 神经酰胺（d18:1/24:1）是来源于鞘氨醇与神经酸（木蜡酸（24：0）的单不饱和类似物）的合成神经酰胺。C24:1 神经酰胺-d7(d18:1-d7/24:1(15Z)) 是C24:1神经酰胺的氘代衍生物 (d18:1/24:1).。
应用
C24:1 神经酰胺-d7 (d18:1-d7/24:1(15Z)) 已被用作液相色谱-质谱法（LC-MS）定量测定骨骼肌中C24:1神经酰胺的标准品。它还被用作通过thermo Q-Exactive四极杆-静电场轨道阱质谱（quadrupole-orbitrap mass spectrometery）测量斑马鱼大脑和人胚胎肾细胞系（HEK293）中C40-C44神经酰胺的标准品。
生化/生理作用
监测人血浆中神经酰胺 (Cer) d18:1/16:0、Cer d18:1/18:0、Cer d18:1/24:0和 Cer d18:1/24:1 的水平及其比率有助于冠状动脉疾病致命结果的预后。稳定同位素形式的C24:1神经酰胺（d18:1/24:1）适用于研究人员新近描述的经过验证的液相色谱-串联质谱方法，用于其临床规模的测量。
包装
5 mL 棕色玻璃螺旋盖小瓶 (860679P-1 mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
闪点(°F)
No data available
闪点(°C)
No data available
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
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