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关于此项目
经验公式（希尔记法）:
C42H74D7NO3
化学文摘社编号:
分子量:
655.14
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
C24:1 神经酰胺-d7 (d18:1-d7/24:1 (15Z)), Avanti Research™ - A Croda Brand 860679P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860679P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860679P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
InChI key
VJSBNBBOSZJDKB-PVDQZAGSSA-N
General description
C24:1 神经酰胺（d18:1/24:1）是来源于鞘氨醇与神经酸（木蜡酸（24：0）的单不饱和类似物）的合成神经酰胺。C24:1 神经酰胺-d7(d18:1-d7/24:1(15Z)) 是C24:1神经酰胺的氘代衍生物 (d18:1/24:1).。
Application
C24:1 神经酰胺-d7 (d18:1-d7/24:1(15Z)) 已被用作液相色谱-质谱法（LC-MS）定量测定骨骼肌中C24:1神经酰胺的标准品。它还被用作通过thermo Q-Exactive四极杆-静电场轨道阱质谱（quadrupole-orbitrap mass spectrometery）测量斑马鱼大脑和人胚胎肾细胞系（HEK293）中C40-C44神经酰胺的标准品。
Biochem/physiol Actions
监测人血浆中神经酰胺 (Cer) d18:1/16:0、Cer d18:1/18:0、Cer d18:1/24:0和 Cer d18:1/24:1 的水平及其比率有助于冠状动脉疾病致命结果的预后。稳定同位素形式的C24:1神经酰胺（d18:1/24:1）适用于研究人员新近描述的经过验证的液相色谱-串联质谱方法，用于其临床规模的测量。
Packaging
5 mL 棕色玻璃螺旋盖小瓶 (860679P-1 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860679P-1MG | 04061835191840 |