形式
powder
包装
pkg of 1 × 1 mg (860678P-1mg)
pkg of 1 × 5 mg (860678P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860678P
运输
dry ice
储存温度
−20°C
一般描述
C24神经酰胺（d18:1/24:0）是一种含有鞘氨醇和木质酸的合成神经酰胺。 神经酰胺合成酶2负责C24 神经酰胺的合成。C24神经酰胺（d18:1-d7/24:0）是C24 神经酰胺（d18:1/24:0）的氘代衍生物 。
应用
C24神经酰胺d7（d18:1-d7/24:0）已被用作液相色谱-质谱联用（LC-MS）法定量分析骨骼肌中C24 神经酰胺的标准品。
生化/生理作用
C24神经酰胺在诱导细胞死亡中起着至关重要的作用。在肿瘤监控中C24神经酰胺水平的变化可能是一个潜在的指标。测定人血浆中神经酰胺 (Cer) d18:1/16:0、Cer d18:1/18:0、Cer d18:1/24:0和Cer d18:1/24:1的水平和比例有助于预测冠状动脉疾病的致命结果。C24神经酰胺 (d18:1/24:0) 的稳定同位素形式可方便地用于经过验证的新液相色谱-串联字谱联用方法进行临床规模的测量。
包装
5 mL 琥珀色玻璃螺旋盖小瓶 (860678P-1 mg)
5 mL 琥珀色玻璃螺旋盖小瓶 (860678P-5 mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Yenisleidy de Las Mercedes Zulueta Díaz et al.
Colloids and surfaces. B, Biointerfaces, 185, 110621-110621 (2019-11-15)
L-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which act as skin permeation enhancers. We investigated the physical changes induced by incorporating ASCn into stratum corneum (SC) lipid membranes and correlated this with the mechanism proposed in
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
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