产品名称
C16 Ceramide (d14:1/16:0), Avanti Research™ - A Croda Brand, powder
InChI
1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-20-22-24-26-30(34)31-28(27-32)29(33)25-23-21-19-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
InChI key
OCXQIBPNDRJADM-VARSQMIESA-N
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCC
assay
99% (TLC)
form
powder
packaging
1 ea of 10 mg (860671P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
deuterated lipids
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Ceramide plays a role in cell signaling processes, such as cell cycle arrest and promotes apoptosis. It is also involved in signal transduction processes and insulin resistance. Ceramide also plays a role in cell proliferation, differentiation and inflammatory responses.
General description
Ceramide is a sphingolipid metabolite. It is composed of sphingosine base linked via amide linkage to a fatty acid.
Packaging
5 mL Amber Glass Screw Cap Vial
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ceramides and skin function
Coderch L, et al.
American Journal of Clinical Dermatology, 4(2), 107-129 (2003)
Ceramide 1-phosphate/ceramide, a switch between life and death
Gomez-Munoz A
Biochimica et Biophysica Acta - Biomembranes, 1758(12), 2049-2056 (2006)
Ceramide and ceramide 1-phosphate in health and disease
Arana L, et al.
Lipids in Health and Disease, 9(1), 15-15 (2010)
Mutay Aslan et al.
Nutrition and cancer, 1-13 (2020-04-15)
We aimed to investigate the impact of thymoquinone (TQ), on sphingolipid metabolites, ER stress and apoptotic pathways in MCF-7 and HepG2 cancer cells. Antiproliferative effect was exerted in cancer cells via TQ incubation at different doses and durations. Cell viability
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