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860668P

Avanti

4E,11Z-Sphingadiene

Avanti Research™ - A Croda Brand 860668P, powder

别名:

(2S,3R,4E,11Z)-2-aminooctadec-4,11-diene-1,3-diol

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About This Item

经验公式（希尔记法）:
C18H35NO2
CAS号:
1975149-81-5
分子量:
297.48
MDL编号:
MFCD32697034
UNSPSC代码:
12352211
NACRES:
NA.25

表单

powder

包装

pkg of 1 × 1 mg (860668P-1mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 860668P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCC/C=C\CCCCCC

InChI

1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h7-8,14-15,17-18,20-21H,2-6,9-13,16,19H2,1H3/b8-7-,15-14+/t17-,18+/m0/s1

InChI key

PZYQAHLJANGLKE-ZLHPJBHGSA-N

相关类别

一般描述

4E,11Z-Sphingadiene is a unique sphingoid base containing trans double bond at C4 and cis double bond at C11 positions along the sphingoid base alkyl chain. Sphingadienes are found in insects, marine organisms, legumes including soybeans and soy products.

应用

4E,11Z-Sphingadiene has been used as a standard in 193 nm ultraviolet photodissociation (UVPD)-ultra high resolution tandem mass spectrometry for its detailed structural characterization.

生化/生理作用

Sphingadienes are growth-inhibitory sphingoid bases, involved in apoptosis and cell signaling. It inhibits Akt/Wnt signaling that might contribute to their chemopreventive properties in colon cancer.

包装

5 mL Amber Glass Screw Cap Vial (860668P-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

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分析证书(COA)

Lot/Batch Number

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Detailed structural characterization of sphingolipids via 193 nm ultraviolet photodissociation and ultrahigh resolution tandem mass spectrometry
Ryan E, et al.
Journal of the American Society For Mass Spectrometry, 28(7), 1406-1419 (2017)
Occurrence, structure elucidation, biosynthesis, functions and synthesis of sphingadienes
U Abeytunga T
Mini-Reviews in Organic Chemistry, 12(3), 282-292 (2015)
Ashok Kumar et al.
Carcinogenesis, 33(9), 1726-1735 (2012-05-15)
Sphingadienes (SDs) derived from soy and other natural sphingolipids are cytotoxic to colon cancer cells via an Akt-dependent mechanism and reduce adenoma formation in Apc(Min/+) mice. Wnt signaling is fundamental to colon carcinogenesis and is the basis for spontaneous tumorigenesis

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