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Merck
CN

860649P

Avanti

C24 Ceramide (d17:1/24:0)

Avanti Research - A Croda Brand 860649P, powder

别名:

N-lignoceroyl-D-erythro-sphingosine (C17 base)

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About This Item

经验公式(希尔记法):
C41H81NO3
分子量:
636.09
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 10 mg (860649P-10mg)

制造商/商品名称

Avanti Research - A Croda Brand 860649P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

一般描述

C24 Ceramide (d17:1/24:0) is a synthetic ceramide derived from a C17 sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide.

应用

C24 Ceramide (d17:1/24:0) has been used as an internal standard to quantify ceramide content in both subcutaneous and visceral adipose tissue by ultraperformance liquid chromatography - tandem mass spectrometery (UPLC-MS/MS).

生化/生理作用

C24 Ceramide (d17:1/24:0) plays a vital role in inducing cell death. Altered levels of C24 Ceramide might be a potential indication in tumor monitoring.

包装

5 mL Amber Glass Screw Cap Vial (860649P-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Agnieszka U Blachnio-Zabielska et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Ceramide accumulation in muscle and in liver is implicated in the induction of insulin resistance. Much less in known about the role of ceramide in adipose tissue. The aim of the present study was to elucidate the role of ceramide
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of

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