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Merck
CN

860648P

Avanti

C20 Ceramide (d17:1/20:0)

Avanti Research - A Croda Brand 860648P, powder

别名:

N-arachidoyl-D-erythro-sphingosine (C17 base)

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About This Item

经验公式(希尔记法):
C37H73NO3
分子量:
579.98
UNSPSC代码:
12352100
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 10 mg (860648P-10mg)

制造商/商品名称

Avanti Research - A Croda Brand 860648P

脂质类型

deuterated lipids
sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

一般描述

C20 Ceramide (d17:1/20:0) is a synthetic ceramide containing C17 analog of sphingosine with arachidonic acid. Ceramide synthase 2 catalyzes the synthesis of C20 Ceramide. Ceramide is the key component of sphingolipids.

应用

C20 Ceramide (d17:1/20:0) has been used as an internal standard to measure the sphingolipid content in liver by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC/MS/MS).

生化/生理作用

Ceramides play an important role in cell signaling, cell differentiation, proliferation and apoptosis.

包装

5 mL Amber Glass Screw Cap Vial (860648P-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available


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Ceramide Structure and Derivatives
Kumari A
Sweet Biochemistry: Remembering Structures, Cycles, and Pathways by Mnemonics (2018)
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of

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