形式
powder
包装
pkg of 1 × 10 mg (860640P-10mg)
pkg of 1 × 5 mg (860640P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860640P
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCC
InChI
1S/C17H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h13-14,16-17,19-20H,2-12,15,18H2,1H3/b14-13+/t16-,17+/m0/s1
InChI key
RBEJCQPPFCKTRZ-LHMZYYNSSA-N
一般描述
鞘氨醇（d17:1）或D-赤型鞘氨醇是一种17碳鞘脂，存在于人体皮肤中。它比天然存在的C18-鞘氨醇少一个碳。
应用
鞘氨醇（d17:1）已被用作脂质标准品，用于通过液相色谱-质谱（LC-MS）和串联质谱法分析鞘脂。
生化/生理作用
鞘氨醇充当鞘氨醇-1-磷酸（S1P）的前体。鞘氨醇C-17用作通过光谱法分析鞘脂的内标物。
包装
5 mL棕色玻璃螺旋盖小瓶（860640P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860640P-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines
Stewart ME and Downing DT
The Journal of Investigative Dermatology, 105(4), 613-618 (1995)
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Schull S, et al.
Cell Death & Disease, 6(3), e1691-e1691 (2015)
A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Paugh SW, et al.
Blood, 112(4), 1382-1391 (2008)
Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells
Apraiz A, et al.
BMC Cancer, 11(1), 477-477 (2011)
Guang-Yi Dai et al.
The Journal of biological chemistry, 295(3), 717-728 (2019-12-11)
Cellular membranes contain many lipids, some of which, such as sphingolipids, have important structural and signaling functions. The common sphingolipid glucosylceramide (GlcCer) is present in plants, fungi, and animals. As a major plant sphingolipid, GlcCer is involved in the formation
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