推荐产品
形式
powder
包装
pkg of 1 × 10 mg (860617P-10mg)
pkg of 1 × 5 mg (860617P-5mg)
制造商/商品名称
Avanti Polar Lipids 860617P
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO
一般描述
Phytosphingosine is a biologically significant saturated long-chain sphingoid base, found in membranes of yeasts, fungi, plants and mammalian epidermis, including the stratum corneum.
应用
N-16:0 Phytosphingosine has been used as a lipid standard in electrospray ionization (ESI)-mass spectrometry (MS)-based lipidomic analysis.
生化/生理作用
Phytosphingosine plays a vital role in the defense mechanism of the skin by exhibiting anti-microbial and anti-inflammatory properties. It elicits keratinocyte differentiation and is therefore, used as an active ingredient in the cosmetic formulations. PHS helps in maintaining the structural integrity of the membranes. It also regulates cellular growth and mediates the heat stress response of yeast.
包装
5 mL Amber Glass Screw Cap Vial (860617P-10mg)
5 mL Amber Glass Screw Cap Vial (860617P-5mg)
WGK
WGK 3
Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome
Makarova M, et al.
Current Biology (2020)
Antimicrobial Activity of Phytosphingosine Nanoemulsions against Bacteria and Yeasts
Bascpinar P, et al.
CBE Life Sciences Education, 14(2), 223-228 (2018)
Polar emollients in cosmetic formulations enhance the penetration and biological effects of Phytosphingosine on skin
Schiemann Y, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 331(1-2), 103-107 (2008)
Asymmetric synthesis of d-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy) acetaldehyde
Liu Z, et al.
The Journal of Organic Chemistry, 75(13), 4356-4364 (2010)
Zheng Liu et al.
The Journal of organic chemistry, 75(13), 4356-4364 (2010-06-10)
An asymmetric synthesis of d-ribo-phytosphingosine (1) was achieved by utilizing the ProPhenol (12)-catalyzed alkynylation of unsaturated aldehyde 8 to afford allylic propargylic alcohol (S)-6 followed by asymmetric epoxidation and opening of propargylic epoxy alcohol anti-5 with NaN(3)/NH(4)Cl. Deprotection and reduction
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