跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

860580C

Avanti

02:0 SM (d18:1/2:0)

Avanti Research™ - A Croda Brand 860580C

别名:

N-acetyl-D-erythro-sphingosylphosphorylcholine

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C25H51N2O6P
CAS号:
148306-05-2
分子量:
506.66
UNSPSC代码:
12352211
NACRES:
NA.25

表单

liquid

包装

pkg of 1 × 1 mL (860580C-5mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 860580C

浓度

5 mg/mL (860580C-5mg)

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(C)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C25H51N2O6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(29)24(26-23(2)28)22-33-34(30,31)32-21-20-27(3,4)5/h18-19,24-25,29H,6-17,20-22H2,1-5H3,(H-,26,28,30,31)/b19-18+/t24-,25+/m0/s1

InChI key

GTZSEZHHSPWFFN-WHUSYDGZSA-N

一般描述

Sphingomyelin (SM) is a major constituent of cell membranes. It is present mainly in the membranes of nerve cells (in the myelin sheaths) and red blood cells. SM contains a ceramide unit with a phosphorylcholine moiety attached to position 1.

应用

02:0 SM (d18:1/2:0) is suitable for use in liposomes to measure ostreolysin A (OlyA) binding in order to infer the effects of phosphatidylcholines (PCs) on sphingomyelin (SM)/cholesterol interactions.

生化/生理作用

Sphingomyelin (SM) has a high affinity for cholesterol. Both together regulate the localization and interactions of proteins. SM acts as a precursor to ceramides and other sphingolipid metabolites. It aids iron transport into cells. SM regulates ion channels and receptors.

包装

5 mL Clear Glass Sealed Ampule (860580C-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

SPHINGOMYELIN AND RELATED LIPIDS
OH, H
Journal of the American Oil Chemists' Society null
Molecular discrimination between two conformations of sphingomyelin in plasma membranes
Endapally S, et al.
Cell, 176(5), 1040-1053 (2019)
Delphine Milhas et al.
FEBS letters, 584(9), 1887-1894 (2009-10-28)
The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门