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表单
powder
包装
pkg of 1 × 10 mg (860512P-10mg)
pkg of 1 × 25 mg (860512P-25mg)
pkg of 1 × 5 mg (860512P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
InChI key
HXFPPRPLRSPNIB-VARSQMIESA-N
一般描述
C12神经酰胺（d18：1/12：0）是一种含有鞘氨醇和十二烷酸的合成神经酰胺。
应用
C12神经酰胺（d18:1/12:0）或N-月桂酰-D-赤型-鞘氨醇已用于：
- 作为脂质标准品，用于优化液相色谱-质谱（LC-MS）法条件
- 作为U87MG（人胶质瘤细胞系）中脂质提取的内标
- 作为液相色谱-质谱（LC-MS）法测定大鼠组织中神经酰胺含量的内标
生化/生理作用
神经酰胺是鞘脂的信号传导，与调节应激反应和炎症有关。它还调节细胞生长停滞、分化和凋亡。
包装
5 mL棕色玻璃螺旋盖小瓶（860512P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-25mg）
5 mL棕色玻璃螺旋盖小瓶（860512P-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
Ismael González-García et al.
Cell reports, 25(2), 413-423 (2018-10-12)
Compelling evidence has shown that, besides its putative effect on the regulation of the gonadal axis, estradiol (E2) exerts a dichotomic effect on the hypothalamus to regulate food intake and energy expenditure. The anorectic effect of E2 is mainly mediated
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main
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