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文件

860461P

Avanti

N-C12-desoxymethylsphinganine

Name: N-C12-desoxymethylsphinganine
Brand: AVANTI

N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder

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别名:

N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959

经验公式（希尔记法）:

C₂₉H₅₉NO₂

CAS号:

1246298-41-8

分子量:

453.78

UNSPSC代码:

12352211

NACRES:

NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 1 mg (860461P-1mg)

制造商/商品名称

Avanti Polar Lipids 860461P

脂质类型

sphingolipids
bioactive lipids

运输

dry ice

储存温度

−20°C

一般描述

Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.

生化/生理作用

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

包装

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

WGK

WGK 3

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