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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (860457P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860457P
脂质类型
sphingolipids
bioactive lipids
运输
dry ice
储存温度
−20°C
一般描述
The sphingoid bases sphingosine is acylated with fatty acids with varying acyl-chain resulting in the synthesis of 1-deoxydihydroceramides (1-deoxyDHCers). These deoxyDHCers are further converted to 1-deoxyceramides (1-deoxysphingosine) and 1-(deoxymethyl)ceramides. They are produced by mammals.
生化/生理作用
The 1-deoxydihydroceramides are hydrophobic and interact with monolayers and giant unilamellar vesicles. They modulate cell membrane and may affect their biological functionality.
包装
5 mL Amber Glass Screw Cap Vial (860457P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Biophysical properties of novel 1-deoxy-(dihydro) ceramides occurring in mammalian cells
Jimenez-Rojo N, et al.
Biophysical Journal, 107(12), 2850-2859 (2014)
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now
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