检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 2.5 mL (860102C-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860102C
浓度
10 mg/mL (860102C-25mg)
运输
dry ice
储存温度
−20°C
InChI
1S/C38H75O8P.Na/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-37(39)43-34-36(35-45-47(41,42)44-33-6-3)46-38(40)32-30-28-26-24-22-20-18-16-14-12-10-8-5-2;/h36H,4-35H2,1-3H3,(H,41,42);/q;+1/p-1/t36-;/m1./s1
InChI key
SKVWIBXHTOHOAB-SKRAEFHRSA-M
一般描述
Phosphatidylpropanol is a low polarity phospholipid. This phosphatidylalcohol can be produced by phospholipase D (PLD) catalyzed transphosphatidylation reaction of phosphatidylcholine (PC) and propanol.
应用
16:0 Phosphatidylpropanol or 1,2-dipalmitoyl-sn-glycero-3-phosphopropanol may be used as an internal standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to evaluate its matrix effect in blood samples for the validation of phosphatidylethanol (PEth). It may also be used as an internal standard for the quantification of PEth using liquid chromatography-mass spectrometry (LC-MS) in human blood.
生化/生理作用
Phosphatidylpropanol acts as a potential biomarker in phospholipase D activity assays.
包装
5 mL Clear Glass Sealed Ampule (860102C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
新产品
Long-term stability of the alcohol consumption biomarker phosphatidylethanol in erythrocytes at- 80? C
Lakso H, et al.
Clinical mass spectrometry, 11(3), 37-41 (2019)
Mikhail Vyssotski et al.
Lipids, 44(4), 381-389 (2008-12-17)
High-performance TLC and (31)P-NMR were assessed as methods of observing the presence of numerous low polarity phospholipids: bis-phosphatidic acid (BPA), semi-lyso bis-phosphatidic acid (SLBPA), N-acyl phosphatidylethanolamine (NAPE), N-(1,1-dimethyl-3-oxo-butyl)-phosphatidylethanolamine (diacetone adduct of PE, DOBPE), N-acetyl PE, phosphatidylmethanol (PM), phosphatidylethanol (PEt), phosphatidyl-n-propanol
Siming Wang et al.
Talanta, 166, 315-320 (2017-02-19)
Phosphatidylethanol (PEth) is a special phospholipid that is only formed in the presence of ethanol, and therefore, serves as a promising biomarker for alcohol intake. In this study, a simple, rapid and precise method based on LC-MS/MS combined with ultrasound-assisted
Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and
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