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文件

安全信息

860080P

Avanti

18:1 Lactosyl PE

Avanti Polar Lipids

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别名:
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)
经验公式（希尔记法）:
C53H103N2O18P
CAS号:
474943-47-0
分子量:
1087.36
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 25 mg (860080P-25mg)
pkg of 1 × 5 mg (860080P-5mg)
pkg of 1 × 50 mg (860080P-50mg)

制造商/商品名称

Avanti Polar Lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP(OCCNCC(O)C(O)[C@@H]([C@H](O)CO)O[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C53H100NO18P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-46(59)67-40-42(70-47(60)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)41-69-73(65,66)68-36-35-54-37-43(57)48(61)52(44(58)38-55)72-53-51(64)50(63)49(62)45(39-56)71-53;/h17-20,42-45,48-58,61-64H,3-16,21-41H2,1-2H3,(H,65,66);1H3/b19-17-,20-18-;/t42-,43?,44?,45?,48?,49+,50?,51?,52-,53+;/m1./s1

InChI key

POKKWVSABAYGGQ-GDPHZLNSSA-N

相关类别

一般描述

Phosphatidylethanolamine is a phospholipid and is bound to the biological membranes.

应用

18:1 Lactosyl PE is suitable for the preparation of donor liposomes.

生化/生理作用

Phosphatidylethanolamine has a tendency of binding to proteins and forming a complex of phosphatidylethanolamine-binding protein (PEBP). The binding of an isoform of phosphatidylethanolamine (1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine) to Peroxisome Proliferator-Activated Receptors (PPARs) helps in regulating genes involved in lipid metabolism.

包装

5 mL Clear Glass Sealed Ampule (860080P-25mg)
5 mL Clear Glass Sealed Ampule (860080P-50mg)
5 mL Clear Glass Sealed Ampule (860080P-5mg)

WGK

WGK 3

法规信息

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A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Bockelmann S, et al.
Journal of Lipid Research, 59(3), 515-530 (2018)
Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Banfield M J, et al.
Structure, 6(10), 1245-1254 (1998)
Phosphatidylcholine?s functions beyond that of a membrane brick
Furse S and De Kroon AIPM
Molecular Membrane Biology, 32(4), 117-119 (2015)
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction

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