产品名称
鸡蛋 SM, Avanti Research™ - A Croda Brand
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChI
1S/C39H79N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-38(42)37(36-47-48(44,45)46-35-34-41(3,4)5)40-39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h30,32,37-38,42H,6-29,31,33-36H2,1-5H3,(H-,40,43,44,45)/b32-30+/t37-,38+/m0/s1
InChI key
RWKUXQNLWDTSLO-GWQJGLRPSA-N
description
Sphingomyelin (Egg, Chicken)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (860061P-1g)
pkg of 1 × 200 mg (860061P-200mg)
pkg of 1 × 25 mg (860061P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
蛋黄SM可用于制备鞘磷脂(SM)标准溶液。还可用于制备脂质体。
General description
作为细胞膜的主要成分,鞘磷脂在神经细胞(髓鞘)膜和红细胞膜中的浓度特别高。以前认为,它是因鞘氨醇碱基的2-酰胺基、3-羟基和4,5-反式双键介导的分子间相互作用而具有与磷脂酰胆碱功能相似的纯结构作用。但是,现在人们认识到,鞘磷脂对胆固醇具有高亲和力,这两种脂质在液体无序相中紧密堆积成液体有序结构域,形成脂质筏。这些膜微结构域被认为是调节蛋白质定位和相互作用的信号转导平台。但是,鞘磷脂不仅是会影响信号传导的脂质筏成分,它还是神经酰胺和其他鞘脂代谢(包括鞘磷脂循环或鞘脂网络)产物的前体。
鞘磷脂和相关脂质
鞘磷脂和相关脂质
Packaging
20 mL透明玻璃螺旋盖样品瓶(860061P-1g)
5 mL棕色玻璃螺旋盖样品瓶(860061P-200mg)
5 mL棕色玻璃螺旋盖样品瓶(860061P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
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Protocols for Enzymatic Fluorometric Assays to Quantify Phospholipid Classes
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Previously we proposed that transmission of the hedgehog signal across the plasma membrane by Smoothened is triggered by its interaction with cholesterol (Luchetti et al., 2016). But how is cholesterol, an abundant lipid, regulated tightly enough to control a signaling
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Membrane viscosity and hydration levels characterize the biophysical properties of biological membranes and are reflected in the rate and extent of solvent relaxation, respectively, of environmentally sensitive fluorophores such as Laurdan. Here, we first developed a method for a time-resolved
Takaaki Matsufuji et al.
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Ceramide is a bioactive lipid with important roles in several biological processes including cell proliferation and apoptosis. Although 3-ketoceramides that contain a keto group in place of the 3-OH group of ceramide occur naturally, ceramide derivatives oxidized at the primary
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