产品名称
Ganglioside GD3 (Bovine Milk), Avanti Research™ - A Croda Brand
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO[C@@]4(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C4)[C@@](NC(
description
GD3 Ganglioside (Milk, Bovine-Ammonium Salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860060P-1mg)
pkg of 1 × 5 mg (860060P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
lipid extracts
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
Ganglioside GD3 (Bovine Milk) is suitable as a lipid standard in Fourier-transform ion cyclotron resonance (FTICR) mass spectrometric analysis and liquid chromatography−mass spectrometry (LC-MS/MS) data analysis.
Biochem/physiol Actions
Gangliosides are involved in neuronal development, neuropathologic processes, receptor interactions with protein hormones, interferon, fibronectin and toxins from bacteria, They are also essential for the development of intestinal immunity by producing intestinal IgA and cytokine.
General description
Gangliosides are glycosphingolipids containing a hydrophobic ceramide and hydrophilic oligosaccharide chain. They are found in various tissues and fluids in vertebrates, especially in human brain and bovine milk. The most common gangliosides in milk are 2NeuAc−2Hex−Cer (GD3) and NeuAc−2Hex−Cer (GM3).
Packaging
5 mL Amber Glass Screw Cap Vial (860060P-1mg)
5 mL Amber Glass Screw Cap Vial (860060P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
法规信息
涉药品监管产品
此项目有
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain
Zhang Y, et al.
Scientific Reports, 6, 25289-25289 (2016)
Intact glycosphingolipidomic analysis of the cell membrane during differentiation yields extensive glycan and lipid changes
Wong M, et al.
Scientific reports, 8(1), 10993-10993 (2018)
Rapid profiling of bovine and human milk gangliosides by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry
Lee H, et al.
International Journal of Mass Spectrometry, 305(2-3), 138-150 (2011)
The role of dietary gangliosides on immunity and the prevention of infection
Rueda R
The British Journal of Nutrition, 98(S1), S68-S73 (2007)
Variation of the ganglioside compositions of human milk, cow?s milk and infant formulas
Pan X L, et al.
Early Human Development, 57(1), 25-31 (2000)
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