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Merck
CN
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文件

858144P

Avanti

18:0 溶血剂 PS

1-stearoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt), powder

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别名:
1-十八烷酰基-sn-甘油-3-磷酸-L-丝氨酸（钠盐）；18:0 LPS; C18 LPS; PS(18:0/0:0); 110725
经验公式（希尔记法）:
C24H47NPO9Na
CAS号:
1246298-16-7
分子量:
547.59
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

形式

powder

包装

pkg of 1 × 1 mg (858144P-1mg)
pkg of 1 × 5 mg (858144P-5mg)

制造商/商品名称

Avanti Polar Lipids 858144P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

相关类别

应用

18：0 Lyso Ps可用于在G蛋白偶联受体174（GPR174）细胞中，刺激细胞内环状单磷酸腺苷（cAMP），使其增加。也可用于基于液相色谱-质谱法（LC-MS）对磷脂酰丝氨酸（PS）氧化/水解分子种类进行结构表征。

包装

5 mL棕色玻璃螺旋盖样品瓶（858144P-1mg）
5 mL棕色玻璃螺旋盖样品瓶（858144P-5mg）

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Kazuya Sugita et al.
Biochemical and biophysical research communications, 430(1), 190-195 (2012-11-28)
We established cell lines that stably express orphan GPCR GPR174 using CHO cells, and studied physiological and pharmacological features of the receptor. GPR174-expressing cells showed cell-cell adhesion with localization of actin filaments to cell membrane, and revealed significant delay of
Vladimir A Tyurin et al.
Biochemistry, 51(48), 9736-9750 (2012-11-15)
Ca(2+)-independent lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a member of the phospholipase A(2) superfamily with a distinguishing characteristic of high specificity for oxidatively modified sn-2 fatty acid residues in phospholipids that has been especially well characterized for peroxidized species of phosphatidylcholines
Ming Zhu et al.
International immunopharmacology, 81, 106034-106034 (2019-12-02)
GPR174 plays a crucial role in immune responses, but the role of GPR174 in the pathological progress of sepsis remains incompletely understood. In this study, we generated a sepsis model by cecal ligation and puncture (CLP) to investigate the role
Masako Nishikawa et al.
Journal of atherosclerosis and thrombosis, 22(5), 518-526 (2014-12-03)
Lysophospholipids, particularly sphingosine 1-phosphate and lysophosphatidic acid, are known to be involved in the pathogenesis of atherosclerosis; however, the role of lysophosphatidylserine (LysoPS) in the onset of atherosclerotic diseases remains uncertain. We investigated the effects of LysoPS on the uptake

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