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Merck
CN

858141P

Avanti

17:1 Lyso PS

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-[phospho-L-serine] (sodium salt), powder

别名:

110724

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About This Item

经验公式(希尔记法):
C23H43NNaO9P
分子量:
531.55
UNSPSC代码:
51191904
NACRES:
NA.25

方案

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

表单

powder

包装

pkg of 1 × 100 mg (858141P-100mg)
pkg of 1 × 5 mg (858141P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 858141P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[Na+]

InChI

1S/C23H44NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22(26)31-17-20(25)18-32-34(29,30)33-19-21(24)23(27)28;/h7-8,20-21,25H,2-6,9-19,24H2,1H3,(H,27,28)(H,29,30);/q;+1/p-1/b8-7-;/t20-,21+;/m1./s1

InChI key

OALJMCAGNYARLY-XZEOLHCOSA-M

应用

17:1 Lyso PS可用作石墨化炭黑-固相萃取(GCB-SPE)方法中脂质提取的标准品。它也可以用作细胞和大脑样品的代谢组学分析中的内标。

生化/生理作用

17:1 Lyso PS可以作为奇数链LIPIDOMIX定量质谱内标。

包装

5 mL透明玻璃密封安瓿(858141P-100mg)
5 mL透明玻璃密封安瓿(858141P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Daisuke Ogasawara et al.
Nature chemical biology, 14(12), 1099-1108 (2018-11-14)
ABHD12 metabolizes bioactive lysophospholipids, including lysophosphatidylserine (lyso-PS). Deleterious mutations in human ABHD12 cause the neurological disease PHARC, and ABHD12-/- mice display PHARC-like phenotypes, including hearing loss, along with elevated brain lyso-PS and features of stimulated innate immune cell function. Here
Michela Antonelli et al.
Analytical and bioanalytical chemistry, 412(2), 413-423 (2019-11-25)
The chemical composition of Cannabis sativa L. has been extensively investigated for several years; nevertheless, a detailed lipidome characterization is completely lacking in the literature. To achieve this goal, an extraction and enrichment procedure was developed for the characterization of
Biyu Hou et al.
Life sciences, 245, 117352-117352 (2020-02-02)
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipose tissue (WAT), which plays a central role in its distinct response to outside stimuli. However, the detailed lipidome of depot-specific
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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