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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 10 mg (857504P-10MG)
pkg of 1 × 5 mg (857504P-5MG)
制造商/商品名称
Avanti Polar Lipids (857504P)
脂质类型
phospholipids
bacterial lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC(C)C)=O)COC(CCCCCCCCCCCCCCC)=O)=O
一般描述
16:0-i15:0 phosphatidylcholine (PC) is an asymmetric saturated PC. Phosphatidylcholine (PC) is one of the major zwitterionic glycerophospholipids of the eukaryotic membranes. PC is synthesized in higher eukaryotes via two pathways namely the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway. PC is a cylindrical shaped molecule.
生化/生理作用
16:0-i15:0 is used in the preparation of liposomes and large unilamellar vesicles. Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. Biosynthesis of PC is essential for normal very low density lipoprotein secretion from hepatocytes. PC is the dominant phospholipid present in cancer and non-neoplastic tissues.
包装
5 mL Amber Glass Screw Cap Vial (857504P-5MG and 857504P-10MG)
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Branched phospholipids render lipid vesicles more susceptible to membrane-active peptides
Mitchell NJ, et al.
Biochimica et biophysica acta. General subjects, 1858(5), 988-994 (2016)
Thematic review series: glycerolipids. Phosphatidylcholine and choline homeostasis
Li Z and Vance DE
Journal of Lipid Research, 49(6), 1187-1194 (2008)
Nobuya Kurabe et al.
Cancer science, 104(10), 1295-1302 (2013-07-03)
The identification of cancer biomarkers is critical for target-linked cancer therapy. The overall level of phosphatidylcholine (PC) is elevated in colorectal cancer (CRC). To investigate which species of PC is overexpressed in colorectal cancer, an imaging mass spectrometry was performed
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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