检测方案
99% (TLC)
形式
powder
包装
pkg of 1 × 1 mg (857382P-1MG)
制造商/商品名称
Avanti Research™ - A Croda Brand
运输
dry ice
储存温度
−20°C
SMILES字符串
N=C(N)N1CC[C@H](O)[C@@H]1C2=NC(C3=CC4=CC=C(OCCCCC)C=C4C=C3)=NO2
一般描述
SLC5111312 is a selective inhibitor of mouse sphingosine kinase 2 (SphK2). It also inhibits rat and human sphingosine kinase type 1 and type 2 (SphK1/2). It is made up of pedant 1-guanidino-2-phenyloxadiazolylpyrrolidine group.
生化/生理作用
SLC5111312 increases the blood sphingosine 1-phosphate (S1P) levels in mice due to the inhibition of sphingosine kinase type 2 (SphK2).
包装
5ML Amber Glass Screw Cap Vial (857382P-1MG)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors
Kharel Y, et al.
PLoS ONE, 13(4), 23-31 (2018)
Sphingosine kinase 2 inhibition and blood sphingosine 1-phosphate levels
Kharel Y, et al.
Journal of Pharmacology and Experimental Therapeutics, 355(1), 23-31 (2015)
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