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方案
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
表单
powder
包装
pkg of 1 × 1 mg (857230P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857230P
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
O[C@](COP([O-])(O)=O)([H])COCCCCCCCC/C=C\CCCCCCCC.[NH4+]
InChI key
WEOSAIXAEGBVPQ-WBIWQBECSA-N
一般描述
C18:1 LPA是一种生物活性脂质。该溶血磷脂酸（LPA）是从膜磷脂中获得的可溶性脂质。它存在于血浆中。
应用
C18:1 LPA适合在萤光素酶测定中刺激人胚胎肾293（HEK 293）细胞。它还适合作为达尔伯克氏改良伊格尔培养基（DMEM）的添加剂，用于跨孔迁移试验、伤口愈合试验和细胞增殖试验。′
生化/生理作用
溶血磷脂酸（LPA）信号转导参与多种细胞过程。它还与神经系统疾病、炎症和癌症有关。
包装
5 mL透明玻璃密封安瓿（857230P-1mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
R D Moreno-Fernández et al.
Neuropharmacology, 164, 107896-107896 (2019-12-08)
The LPA1 receptor, one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts, is likely involved in promoting normal emotional behaviours. Current data suggest that the LPA-LPA1-receptor pathway may be involved in mediating the negative consequences
Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice
Srikanth M, et al.
European Journal of Pharmacology, 841, 49- 56 (2018)
Autotaxin is a novel target of micro RNA-101-3p
Wang Y, et al.
FEBS Open Bio, 9(4), 707- 716 (2019)
Jesica R Williams et al.
The Journal of biological chemistry, 284(25), 17304-17319 (2009-04-16)
Lysophosphatidic acid (LPA) is a ligand for LPA(1-3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4-8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship (SAR) of GPR92/LPA(5) is limited and whether LPA is its
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