产品名称
C18:1 LPA, 1-(9Z-octadecenyl)-2-hydroxy-sn-glycero-3-phosphate (ammonium salt), powder
InChI key
WEOSAIXAEGBVPQ-WBIWQBECSA-N
SMILES string
O[C@](COP([O-])(O)=O)([H])COCCCCCCCC/C=C\CCCCCCCC.[NH4+]
assay
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
form
powder
packaging
pkg of 1 × 1 mg (857230P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857230P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
Application
C18:1 LPA适合在萤光素酶测定中刺激人胚胎肾293（HEK 293）细胞。它还适合作为达尔伯克氏改良伊格尔培养基（DMEM）的添加剂，用于跨孔迁移试验、伤口愈合试验和细胞增殖试验。′
Biochem/physiol Actions
溶血磷脂酸（LPA）信号转导参与多种细胞过程。它还与神经系统疾病、炎症和癌症有关。
General description
C18:1 LPA是一种生物活性脂质。该溶血磷脂酸（LPA）是从膜磷脂中获得的可溶性脂质。它存在于血浆中。
Packaging
5 mL透明玻璃密封安瓿（857230P-1mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
R D Moreno-Fernández et al.
Neuropharmacology, 164, 107896-107896 (2019-12-08)
The LPA1 receptor, one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts, is likely involved in promoting normal emotional behaviours. Current data suggest that the LPA-LPA1-receptor pathway may be involved in mediating the negative consequences
Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice
Srikanth M, et al.
European Journal of Pharmacology, 841, 49- 56 (2018)
Autotaxin is a novel target of micro RNA-101-3p
Wang Y, et al.
FEBS Open Bio, 9(4), 707- 716 (2019)
Jesica R Williams et al.
The Journal of biological chemistry, 284(25), 17304-17319 (2009-04-16)
Lysophosphatidic acid (LPA) is a ligand for LPA(1-3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4-8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship (SAR) of GPR92/LPA(5) is limited and whether LPA is its
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