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描述
1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
方案
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
表单
powder
包装
pkg of 1 × 200 mg (857123P-200mg)
pkg of 1 × 25 mg (857123P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
一般描述
溶血磷脂酸（LPA）属于磷脂类，其甘油主链由磷酸基、脂肪链和羟基连接而成。它的磷酸基连接到sn-3位，脂肪链连接到sn-1或sn-2位，羟基连接到其余sn-1或sn-2位。
应用
16:0 Lyso PA适合用作从卵巢癌患者血浆样品中提取脂质的内标。它也适合于制备用于合成脂质体的脂质溶液。
生化/生理作用
溶血磷脂酸（LPA）参与多种生物学功能。它是检测卵巢癌的潜在生物标志物。LPA可刺激血小板聚集、平滑肌收缩、趋化、细胞骨架重排、Ca2+动员、神经递质释放和细胞增殖。棕榈酰溶血磷脂酸会增加二磷酸腺苷（ADP）刺激的聚集。
包装
5 mL棕色玻璃螺旋盖样品瓶（857123P-200mg）
5 mL棕色玻璃螺旋盖样品瓶（857123P-25mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
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Langmuir : the ACS journal of surfaces and colloids, 36(17), 4671-4681 (2020-04-10)
Amyloid fibrils are formed by denatured proteins when the supersaturation of denatured proteins is broken by agitation, such as ultrasonication, or by seeding, although the detailed mechanism of how solubility and supersaturation regulate amyloid formation remains unclear. To further understand
Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column
Shan L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 22-28 (2008)
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
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