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Merck
CN

855810P

Avanti

26:0 溶血 PC

1-hexacosanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

别名:

1-十六烷酰基-sn-甘油-3-磷酸胆碱;PC(26:0/0:0)

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About This Item

经验公式(希尔记法):
C34H70NO7P
分子量:
635.90
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

形式

powder

包装

pkg of 1 × 10 mg (855810P-10mg)
pkg of 1 × 25 mg (855810P-25mg)
pkg of 1 × 5 mg (855810P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 855810P

运输

dry ice

储存温度

−20°C

一般描述

溶血磷脂酰胆碱(LPC)是一种具有生物活性的促炎脂质,其极性头部含有胆碱基团。它是由病理反应产生的。

应用

26:0 Lyso PC可用作提取C26:0-溶血磷脂酰胆碱(LPC)的内标。

生化/生理作用

溶血磷脂酰胆碱(LPC)诱导许多第二信使,包括蛋白激酶C、细胞外信号调节激酶和蛋白酪氨酸激酶。它可改变不同类型细胞的各种生物学功能,包括内皮细胞、平滑肌细胞、单核细胞、巨噬细胞和T细胞。LPC与动脉粥样硬化和炎性疾病有关。

包装

5 mL棕色玻璃螺旋盖样品瓶(855810P-10mg)
5 mL棕色玻璃螺旋盖样品瓶(855810P-25mg)
5 mL棕色玻璃螺旋盖样品瓶(855810P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


分析证书(COA)

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Xinying Hong et al.
Genetics in medicine : official journal of the American College of Medical Genetics (2020-04-21)
To develop a multiplexed assay for the newborn screening of lysosomal storage disorders and additional inborn errors in a flexible, comprehensive, and affordable manner to keep up with the expansion of the newborn screening panel. Ultraperformance liquid chromatography-tandem mass spectrometry
A thyroid hormone-based strategy for correcting the biochemical abnormality in X-linked adrenoleukodystrophy
Hartley MD, et al.
Endocrinology, 158(5), 1328-1338 (2017)
Analysis of phospholipid species in rat peritoneal surface layer by liquid chromatography/electrospray ionization ion-trap mass spectrometry
Gao F, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1761(7), 667-676 (2006)
Kelsey B Law et al.
Autophagy, 13(5), 868-884 (2017-05-20)
Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)

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