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Merck
CN

855775C

Avanti

18:0 Lyso PC

1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

别名:

1-octadecanoyl-sn-glycero-3-phosphocholine; PC(18:0/0:0)

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About This Item

经验公式(希尔记法):
C26H54NO7P
CAS号:
分子量:
523.68
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

方案

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (855775C-25mg)
pkg of 1 × 20 mL (855775C-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 855775C

浓度

10 mg/mL (855775C-25mg)
25 mg/mL (855775C-500mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(O)COC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3

InChI key

IHNKQIMGVNPMTC-UHFFFAOYSA-N

应用

18:0 Lyso PC has been used in gametocytogenesis assay.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (855775C-500mg)
5 mL Clear Glass Sealed Ampule (855775C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

危险化学品
易制毒化学品(2类)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum
Brancucci NMB, et al.
Cell, 171(7), 1532-1544 (2017)
Anthony J Valente et al.
Free radical biology & medicine, 70, 117-128 (2014-02-25)
Oxidized low-density lipoprotein (oxLDL) induces endothelial cell death through the activation of NF-κB and AP-1 pathways. TRAF3IP2 is a redox-sensitive cytoplasmic adapter protein and an upstream regulator of IKK/NF-κB and JNK/AP-1. Here we show that oxLDL-induced death in human primary
Otto K Kari et al.
Nanoscale, 12(3), 1728-1741 (2020-01-03)
Methodological constraints have limited our ability to study protein corona formation, slowing nanomedicine development and their successful translation into the clinic. We determined hard and soft corona structural properties along with the corresponding proteomic compositions on liposomes in a label-free
Dumindika A Siriwardane et al.
International journal of pharmaceutics, 578, 119077-119077 (2020-01-29)
Identification and quantification of excipient related degradation products in the liposomal formulation is important, as they may impact the safety and efficacy of the drug. Phospholipids are one of the major excipients in liposome drugs composing the lipid bilayer, and
Ieva Ailte et al.
Scientific reports, 6, 30336-30336 (2016-07-28)
Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells

商品

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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