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Merck
CN

855675P

Avanti

16:0 Lyso PC

Avanti Research - A Croda Brand

别名:

1-十六烷酰基-sn-甘油-3-磷酸胆碱;PC(16:0/0:0)

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About This Item

经验公式(希尔记法):
C24H50NO7P
CAS号:
分子量:
495.63
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine

方案

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

表单

powder

包装

pkg of 1 × 1 g (855675P-1g)
pkg of 1 × 200 mg (855675P-200mg)
pkg of 1 × 25 mg (855675P-25mg)
pkg of 1 × 500 mg (855675P-500mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key

ASWBNKHCZGQVJV-HSZRJFAPSA-N

应用


  • Microbubble-Mediated Drug Delivery: 16:0 Lyso PC 在药物输送系统微泡技术开发中的作用揭示了其在药物制剂方面的潜在价值,提高了靶向治疗应用的效率——特别是在癌症治疗中(Aron et al., 2019)。

  • Photodynamic Therapy for Glioma: 本研究涉及在光激活治疗生物混合系统背景下的 16:0 Lyso PC ,证明了其在医学治疗中的应适用性用——特别是通过光动力疗法治疗神经胶质瘤等复杂疾病——揭示了其在增强临床结果方面的潜在作用(Inglut et al., 2019)。

包装

20 mL 透明玻璃螺纹口小瓶(855675P-1g)
20 mL 透明玻璃螺纹口小瓶(855675P-500mg)
5 mL 棕色玻璃螺纹口样品瓶(855675P-200mg)
5 mL 棕色玻璃螺纹口样品瓶(855675P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Takafumi Enomoto et al.
Langmuir : the ACS journal of surfaces and colloids, 34(3), 750-755 (2017-10-06)
A major goal of synthetic biology is the development of rational methodologies to construct self-assembling non-natural membranes, which could enable the efficient fabrication of artificial cellular systems from purely synthetic components. However, spatiotemporal control of artificial membrane formation remains both
Xinyuan Li et al.
Redox biology, 28, 101373-101373 (2019-11-16)
It has been shown that anti-inflammatory cytokines interleukin-35 (IL-35) and IL-10 could inhibit acute endothelial cell (EC) activation, however, it remains unknown if and by what pathways IL-35 and IL-10 could block atherogenic lipid lysophosphatidylcholine (LPC)-induced sustained EC activation; and
Yoko Shima et al.
The Journal of biological chemistry, 295(20), 6983-6991 (2020-04-10)
Newly synthesized major histocompatibility complex (MHC) class I proteins are stabilized in the endoplasmic reticulum (ER) by binding 8-10-mer-long self-peptide antigens that are provided by transporter associated with antigen processing (TAP). These MHC class I:peptide complexes then exit the ER
Li V Yang et al.
Blood, 105(3), 1127-1134 (2004-09-24)
G2A is a G-protein-coupled receptor (GPCR) involved in immune regulation. Previous studies have shown that lysophosphatidylcholine (LPC), a bioactive lipid associated with atherosclerosis and autoimmunity, acts through G2A to induce diverse biologic effects. Production of LPC during cell apoptosis serves
Anthony J Valente et al.
Free radical biology & medicine, 70, 117-128 (2014-02-25)
Oxidized low-density lipoprotein (oxLDL) induces endothelial cell death through the activation of NF-κB and AP-1 pathways. TRAF3IP2 is a redox-sensitive cytoplasmic adapter protein and an upstream regulator of IKK/NF-κB and JNK/AP-1. Here we show that oxLDL-induced death in human primary

商品

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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