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方案
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
表单
powder
包装
pkg of 1 × 200 mg (855475P-200mg)
pkg of 1 × 25 mg (855475P-25mg)
pkg of 1 × 500 mg (855475P-500mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 855475P
运输
dry ice
储存温度
−20°C
SMILES字符串
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O
InChI
1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1
InChI key
BWKILASWCLJPBO-LJQANCHMSA-N
一般描述
溶血磷脂酰胆碱(LPC)是一种在病理反应中分泌的具有生物活性的促炎脂质。它在其极性头部有一个胆碱基团。溶血磷脂酰胆碱(Lyso-PC)是血浆、血管组织和脂蛋白的成分。
应用
12:0 Lyso PC已用于研究其神经形成活性和外源性脂质的应用。
生化/生理作用
溶血磷脂酰胆碱(LPC)改变不同细胞类型的各种功能,例如内皮细胞,平滑肌细胞,单核细胞,巨噬细胞和T细胞。它与动脉硬化症和炎症性疾病有关。LPC激活许多第二信使,包括蛋白激酶C、细胞外信号调节激酶和蛋白酪氨酸激酶。
包装
20 mL透明玻璃螺旋盖小瓶(855475P-500mg)
5 mL棕色玻璃螺旋盖小瓶(855475P-200mg)
5 mL棕色玻璃螺旋盖小瓶(855475P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Inner/outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis
Fichtman B, et al.
Molecular Biology of the Cell, 21(23) (2010)
Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor
Ikeno Y, et al.
Test, 280(30) (2005)
Boris Fichtman et al.
Molecular biology of the cell, 21(23), 4197-4211 (2010-10-12)
Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exchange. The mechanism of nuclear pore assembly involves a unique challenge, as it requires creation of a long-lived membrane-lined channel connecting the inner
Shi-Yuan Wen et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 69, 152690-152690 (2018-11-06)
Rhodioloside is a glucoside of tyrosol isolated from Rhodiola rosea. However, its regulating effect on hepatic dyslipidemia of atherogenic mice has rarely been studied. The specific aims of current study included to clarify lipidomic perturbation in liver tissues of apolipoprotein
Analysis of phospholipid species in rat peritoneal surface layer by liquid chromatography/electrospray ionization ion-trap mass spectrometry
Gao F, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1761(7), 667-676 (2006)
商品
The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn
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