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Merck
CN

852758P

Avanti

C18(血浆)-18:1 PE

1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder

别名:

1-O-1′-(Z)-十八烯基-2--(9Z-十八烯酰基)-sn-甘油-3-磷酸乙醇胺;GPEtn(18:0p/18:1(9Z));110645

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About This Item

经验公式(希尔记法):
C41H80NO7P
分子量:
730.05
UNSPSC代码:
51191904
NACRES:
NA.25

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 10 mg (852758P-10mg)
pkg of 1 × 5 mg (852758P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 852758P

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O

InChI

1S/C41H80NO7P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-46-38-40(39-48-50(44,45)47-37-35-42)49-41(43)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h18,20,33,36,40H,3-17,19,21-32,34-35,37-39,42H2,1-2H3,(H,44,45)/b20-18-,36-33-/t40-/m1/s1

InChI key

XVYPOHCSLJZFED-QZEVRULJSA-N

一般描述

磷脂酰乙醇胺是一种氨基磷脂,存在于真核和原核细胞中。它是生物膜中最丰富的甘油磷脂之一。磷脂酰乙醇胺存在于神经组织中。

应用

C18(血浆)-18:1 PE已用于脂质纯化和脂肪酸提取。它也被用于脂多糖(LPS)介导的富含β的朊病毒蛋白PrPβ转化。

生化/生理作用

磷脂酰乙醇胺形成纯脂质结构。它保持真核细胞膜的流动性。磷脂酰乙醇胺在自噬、细胞分裂和蛋白质折叠中起重要作用。它是合成各种蛋白质修饰的前体。磷脂酰乙醇胺是合成甘油磷脂类的中间体。

包装

5 mL棕色玻璃密封安瓿(852758P-10mg)
5 mL棕色玻璃螺旋盖小瓶(852758P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lipopolysaccharide induced conversion of recombinant prion protein
Saleem F, et al.
Prion, 8(2), 221-232 (2014)
The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry
Takashima S, et al.
Molecular Genetics and Metabolism, 120(3), 255-268 (2017)

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