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描述
1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 5 mL (852758C-10mg)
pkg of 1 × 5 mL (852758C-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
浓度
1 mg/mL (852758C-5mg)
2 mg/mL (852758C-10mg)
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O
InChI key
XVYPOHCSLJZFED-QZEVRULJSA-N
一般描述
Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in the biological membranes. It is found in nervous tissue.
应用
C18(Plasm)-18:1 PE has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS).
生化/生理作用
Phosphatidylethanolamine forms pure lipid structures, which regulate membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a major role in autophagy, cell division and protein folding. It functions as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine acts as an intermediate for the synthesis of glycerophospholipid classes.
包装
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-10mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
靶器官
Liver,Kidney, Respiratory system
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
危险化学品
易制毒化学品（2类）
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
The Membranes of Cells (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Ana West et al.
The journal of physical chemistry. B, 124(5), 828-839 (2020-01-10)
Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here
Geoffrey P Noble et al.
Biochemistry, 54(5), 1180-1187 (2015-01-15)
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in vitro.
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