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Merck
CN

850795C

Avanti

18:3 PE

1,2-dilinolenoyl-sn-glycero-3-phosphoethanolamine, chloroform

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别名:
1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine; PE(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z))
经验公式(希尔记法):
C41H70NO8P
CAS号:
分子量:
735.97
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850795C-25mg)

制造商/商品名称

Avanti Polar Lipids 850795C

浓度

10 mg/mL (850795C-25mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCC/C=C\C/C=C\C/C=C\CC)=O

一般描述

Phosphatidylethanolamine (PE) is a membrane phospholipid. The types of PE depends on the combination of free fatty acids on the α and β position. PE represents the main phospholipid class bacteria and the second most abundant in eukaryotic cells. PE is zwitterionic. PE is synthesized by Kennedy pathway.

应用

18:3 PE has been used in the preparation of liposomes. It may be suitable for use in the characterization of contact angle in monolayer formation.

生化/生理作用

Phosphatidylethanolamine (PE) plays a key role in autophagy, apoptosis, membrane fusion, cell cycle and cognitive function. PE is essential for maintaining membrane architecture. PE functions to monitor proper progression of cytokinesis during cell division. PE is the precursor for many biologically active signaling molecules like diacylglycerol and phosphatidic acid.

包装

5 mL Clear Glass Sealed Ampule (850795C-25mg)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

易制毒化学品(2类)
危险化学品

分析证书(COA)

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Ahu Arslan Yildiz et al.
Colloids and surfaces. B, Biointerfaces, 103, 510-516 (2012-12-25)
A facile method for assembly of biomimetic membranes serving as a platform for expression and insertion of membrane proteins is described. The membrane architecture was constructed in three steps: (i) assembly/printing of α-laminin peptide (P19) spacer on gold to separate
Force-from-lipids gating of mechanosensitive channels modulated by PUFAs
Ridone P, et al.
Journal of the Mechanical Behavior of Biomedical Materials, 79, 158-167 (2018)
Biomimetic membrane platform: fabrication, characterization and applications
Yildiz AA, et al.
Colloids and Interface Science Communications, 103, 510-516 (2013)
Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells
Kaku Y, et al.
Cellular Signalling, 27(9), 1713-1719 (2015)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)

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