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Merck
CN

850700C

Avanti

10:0 PE

1,2-didecanoyl-sn-glycero-3-phosphoethanolamine, chloroform

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别名:
PE(10:0/10:0)
经验公式(希尔记法):
C25H50NO8P
分子量:
523.64
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850700C-25mg)

制造商/商品名称

Avanti Polar Lipids 850700C

浓度

10 mg/mL (850700C-25mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O

一般描述

1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (10:0 PE) is a soluble short-chain phospholipid.

应用

1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (10:0 PE) may be used as an internal standard for the quantitative analysis of phospholipids by electrospray ionization-tandem mass spectrometry (ESI-MS/MS). It may also be used to titrate the lantibiotic cinnamycin (Ro 09-0198) in isothermal titration calorimetry.

生化/生理作用

Phosphatidylethanolamine (PE) controls membrane fluidity in eukaryotic cells.

包装

5 mL Clear Glass Sealed Ampule (850700C-25mg)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

易制毒化学品(2类)
危险化学品

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Gia Machaidze et al.
Biochemistry, 42(43), 12570-12576 (2003-10-29)
Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE). Formation of a complex with phosphatidylethanolamine follows a 1:1 stoichiometry. Using high-sensitivity isothermal titration calorimetry (ITC), we have measured the thermodynamic parameters of complex formation for
J D Cortese et al.
Biochemistry, 26(17), 5283-5293 (1987-08-25)
D-beta-Hydroxybutyrate dehydrogenase (BDH) is a lecithin-requiring mitochondrial enzyme that catalyzes the interconversion of beta-hydroxybutyrate and acetoacetate. The purified soluble enzyme devoid of lipid (i.e., the apodehydrogenase) can be reactivated with soluble lecithin or by insertion into phospholipid vesicles containing lecithin.
Shohei Kotani et al.
Fungal genetics and biology : FG & B, 96, 1-11 (2016-10-22)
In mammals, cytosolic phospholipases A2 (cPLA2s) play important physiological roles by releasing arachidonic acid, a precursor for bioactive lipid mediators, from the biological membranes. In contrast, fungal cPLA2-like proteins are much less characterized and their roles have remained elusive. AoPlaA
Rosie Dawaliby et al.
The Journal of biological chemistry, 291(7), 3658-3667 (2015-12-15)
Adequate membrane fluidity is required for a variety of key cellular processes and in particular for proper function of membrane proteins. In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desaturation and cholesterol, although some

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