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Merck
CN

850699C

Avanti

08:0 PE

1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine, chloroform

别名:

PE(8:0/8:0)

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About This Item

经验公式(希尔记法):
C21H42NO8P
CAS号:
分子量:
467.53
UNSPSC代码:
12352211
NACRES:
NA.25

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (850699C-10mg)
pkg of 1 × 2.5 mL (850699C-25mg)
pkg of 1 × 20 mL (850699C-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 850699C

浓度

10 mg/mL (850699C-10mg)
10 mg/mL (850699C-25mg)
25 mg/mL (850699C-500mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O

InChI key

UNACBKDVIYEXSL-LJQANCHMSA-N

一般描述

Phosphoethanolamine (PE), a lipid chaperone, usually seen in the membrane leaflet is abundantly present in the mitochondria.

应用

08:0 PE (1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine) may be used in the preparation of liposomes for conjugating with pH sensors for live cell imaging. It may also be used in the micelles for kinetic measurements studies. It has been used as a phosphoethanolamine (PE) lipid species in the lipid collision cross section (CCS) calibration mixture.

生化/生理作用

Phosphoethanolamine (PE) participates in phospholipid metabolism. It has the ability to induce nutrient starvation tolerance. PE is capable of stimulating the development of tumor. It actively participates in the production of glycosylphosphatidylinositol-anchored proteins (GPI-AP).

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850699C-500mg)
5 mL Clear Glass Sealed Ampule (850699C-10mg)
5 mL Clear Glass Sealed Ampule (850699C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

危险化学品
易制毒化学品(2类)

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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S K Han et al.
The Journal of biological chemistry, 272(6), 3573-3582 (1997-02-07)
Recent genetic and structural studies have shed considerable light on the mechanism by which secretory phospholipases A2 interact with substrate aggregates. Electrostatic forces play an essential role in optimizing interfacial catalysis. Efficient and productive adsorption of the Class I bovine
Jungju Yoon et al.
Advanced materials (Deerfield Beach, Fla.), 26(26), 4559-4564 (2014-05-03)
Phase separation in films of phospholipids and conjugated polymers results in nanoassemblies because of a difference in the physicochemical properties between the hydrophobic polymers and the polar lipid heads, together with the comparable polymer side-chain lengths to lipid tail lengths
Tsuyoshi Osawa et al.
Cell reports, 29(1), 89-103 (2019-10-03)
Tolerance to severe tumor microenvironments, including hypoxia and nutrient starvation, is a common feature of aggressive cancer cells and can be targeted. However, metabolic alterations that support cancer cells upon nutrient starvation are not well understood. Here, by comprehensive metabolome
Ronja Marie Kühnel et al.
The Analyst, 144(9), 3030-3037 (2019-03-23)
The design of ion sensors has gained importance for the study of ion dynamics in cells, with fluorescent proton nanosensors attracting particular interest because of their applicability in monitoring pH gradients in biological microcompartments and reconstituted membrane systems. In this
D W Ellison et al.
Brain research, 417(2), 389-392 (1987-08-11)
Measurements of both phosphoethanolamine (PEA) and ethanolamine (EA) were made in postmortem brain samples from patients with Alzheimer's disease (AD) and Huntington's disease (HD) using high-performance liquid chromatography with electrochemical detection. In AD levels of PEA were significantly reduced by

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